Case Study

Silver Nanoparticles for Antibacterial Coating in Hospital Equipment

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Overview

Silver nanoparticle-embedded polymer coating for high-touch medical equipment surfaces to reduce hospital-acquired infections.

Infection Control / Antimicrobial Coating

Hospital-Acquired Infections (HAIs) - MRSA, E. coli, P. aeruginosa

Experimental Conditions

Lab testing: ASTM E2149 antimicrobial test. Field trials: 3 hospital ICUs, 6-month deployment, daily cleaning protocols.

Results & Findings

99.9% reduction in MRSA, E. coli, and P. aeruginosa within 2 hours. 45% reduction in HAIs in field trials. Coating durability: 12+ months.
Bacterial Reduction: 99.9% within 2 hours HAI Reduction: 45% in field trials Durability: 12+ months Cleaning Cycles: 1000+ cycles tested Cost Effectiveness: ROI: 3:1 (cost savings vs HAI treatment)

Bacterial reduction: p < 0.0001 vs control (n=30 replicates). HAI reduction: p = 0.003 vs untreated surfaces (n=3 ICUs).

Successful

Insights

Balancing antimicrobial efficacy with coating durability. Ensuring compatibility with hospital cleaning chemicals.
Regulatory approval process. Expansion to other medical devices. Investigation of antiviral properties.

Safety Considerations

No cytotoxicity to human fibroblasts (ISO 10993-5). Silver ion release well below EPA safety limits. Skin contact safety confirmed.

References

  1. Lee et al., ACS Applied Materials & Interfaces, 2024
  2. ASTM E2149 Standard Test Method
  3. ISO 10993-5 Biocompatibility Testing
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Views 340
Published Jan 2026
Updated 1 day ago

How to Cite This Case Study

APA

Medic Tech. (2026). Silver Nanoparticles for Antibacterial Coating in Hospital Equipment. Retrieved from https://protoly.net/case-studies/view/silver-nanoparticles-antibacterial-coating

MLA

Medic Tech. "Silver Nanoparticles for Antibacterial Coating in Hospital Equipment." 2026. Web. 12 Jan 2026.

Chicago

Medic Tech. "Silver Nanoparticles for Antibacterial Coating in Hospital Equipment." Accessed January 12, 2026. https://protoly.net/case-studies/view/silver-nanoparticles-antibacterial-coating.